It happened on I-26 eastbound at exit 107 around 3:56 am.
According to the coroner??s office, 31-year-old Miranda Senn of West Columbia was driving a moped when she was struck by an unknown vehicle which left the scene.
Senn was pronounced dead at the scene.
The accident remains under investigation by the Lexington County Coroner??s Office and the South Carolina Highway Patrol.